BackgroundCurrent policies regulating the use of animals for scientific purposes are based on balancing between potential gain of knowledge and suffering of animals used in experimentation. The balancing process is complicated, on the one hand by plurality of views on our duties towards animals, and on the other hand by more recent discussions on uncertainty in the probability of reaching the final aim of the research and problems of translational failure.MethodsThe study combines ethical analysis based on a literature review with (...) neuropsychiatry-related preclinical research as a case study.ResultsBased on the analysis and the case study we show that neuropsychiatry-related preclinical research is an especially interesting case from an ethical perspective. The 3R principles are used to minimize the negative consequences for the animals used in research. However, neuropsychiatric research is characterized by specific challenges in assessing the probability of success of reaching the final aim, due to our limited mechanistic knowledge of human neuropsychiatric illness. Consequently, the translational value of the currently used animal models may be difficult to prove, which undermines the validity of these models and complicated the ethical assessment.ConclusionsWe conclude that a combined approach that deals with both science and the ethical dimensions is necessary to address the problems of validity and translation in neuropsychiatry-related preclinical research. We suggest this approach to comprise first, improved experimental methods, e.g. by using systematic reviews, second, a more patients-based approach that leads to models that reflect interindividual variation better, and third, more interdisciplinary cooperation. (shrink)

The fundamental tenet of contemporary sociobiology, namely the assumption of a single process of evolution involving the selection of genes, is critically examined. An alternative multiple-level, multiple-process model of evolution is presented which posits that the primary process that operates via selection upon the genes cannot account for certain kinds of biological phenomena, especially complex, learned, social behaviours. The primary process has evolved subsidiary evolutionary levels and processes that act to bridge the gap between genes and these complex behaviours. The (...) subsidiary levels are development, individual animal learning, and socioculture itself. It is argued that individual learning is pivotal to the derivation and biological analysis of culture. The differences between cultural and noncultural societies are stressed. It is concluded that such a multiple-level model of evolution can form the basis for reconciling opposing sides in the sociobiology debate. (shrink)

What are the processes, from conception to adulthood, that enable a single cell to grow into a sentient adult? Neuroconstructivism is a pioneering 2 volume work that sets out a whole new framework for considering the complex topic of development, integrating data from cognitive studies, computational work, and neuroimaging.

There are few moments in human history where the forces of religion, culture and politics converge to produce some of the most significant philosophical ideas in the world. India in the early 20thcentury was one of these moments, where we saw the rise of activist-thinkers like Nehru, Jinnah and Gandhi; individuals who not only liberated human lives but their minds as well. One of most influential members of the group was the poet-philosopher Muhammad Iqbal. Commonly known as the "spiritual father (...) of Pakistan", the philosophical and political ideas of Iqbal not only shaped the face of Indian Muslim nationalism but also shaped the direction of modernist reformist Islam around the world. Bringing together a diverse number of prominent and emerging scholars, from backgrounds in political science, philosophy and religious studies, this book offers novel examinations of the philosophical ideas that laid at the heart of Iqbal's own As such, by producing new developments in research on Iqbal's thought from a diversity of prominent and emerging voices within American and European Islamic studies, this text will offer new and novel examinations of the ideas that lies at the heart of Iqbal's own thought: religion, science, metaphysics, nationalism and religious identity. In our text, the reader will (re)discover many new connections between the "Sage of the Ummah" to the greatest thinkers and ideas of European and Islamic philosophies. (shrink)

Originally published in 1913, this book charts the development, growth and legacy of the schools of the Jansenists of Port-Royal based in Paris. The Port-Royalists used many innovative teaching methods in the years before they were closed down in the mid-seventeenth century, such as their use of the vernacular and their views on the role of the teacher, and Barnard examines the place that the Port-Royalists held in the context of French education more generally to illustrate their lasting influence on (...) other schools. This book will be of value to anyone with an interest in Jansenism and the history of education. (shrink)

Branner, H.C. Humanismens krise.--Hansen, Martin A. Eneren og massen.

Originally published in 1918, this book contains edited English translations of French texts written by the Jansenist inhabitants of Port-Royal during the seventeenth century. Barnard provides an introduction with historical background to the state of education in France at the time, and annotates each translation with pertinent historical and literary references. This book will be of value to anyone with an interest in the history of education and the history of faith schools.

_Psychological Types_ is one of Jung's most important and most famous works. First published by Routledge in the early 1920s it appeared after Jung's so-called fallow period, during which he published little, and it is perhaps the first significant book to appear after his own confrontation with the unconscious. It is the book that introduced the world to the terms 'extravert' and 'introvert'. Though very much associated with the unconscious, in _Psychological Types_ Jung shows himself to be a supreme theorist (...) of the conscious. In putting forward his system of psychological types Jung provides a means for understanding ourselves and the world around us: our different patterns of behaviour, our relationships, marriage, national and international conflict, organizational functioning. Appearing in paperback for the first time this central volume from Jung's Collected Works will be essential to anyone requiring a proper understanding of Jung's psychology. (shrink)

In this book Professor Baldry describes this development from Homer to Cicero when, although the traditional divisions and prejudices still remained string, the ...

First Published in 2007. Routledge is an imprint of Taylor & Francis, an informa company.

This is a posthumous work of one of the "new conservatives." Weaver criticizes what is both new and bad in modernity. There is no concern here for method. The phenomena are seen from the point of view of the concerned citizen. The remarks on total war are probably the most perceptive part of the book.—H. C.

After a discussion of the possible connections between quantum mechanics and consciousness, and an examination of the circumstances under which some properties of a macroscopic system may be described by a quantum mechanical wave function, we propose three types of experiments in which one may search for the possible existence of quantal interference in mental events.

Classical and quantal physics are fundamentally different in the way that each deals with complexity. We examine both the algorithmic and the computational aspects of this difference. Any comprehensive deterministic theory must contain a certain ineffectiveness in producing long-term predictions of the future, whereas a probabilistic theory is not so handicapped. The relevance of these considerations to chaos is discussed.